Benefits of Silica Gel Chromatography

Chromatography is a more popular method which is used in several laboratories and industries for separating several components of a mixture or solution. It is precisely used for separating complex components that have more or less similar chemical and physical properties. Silica gel chromatography is a process which is increasingly popular due to the benefits it gives. Silica gel is a good quality desiccant that is used extensively in chromatography for separation of chemical due to its exceptional water adsorption properties. 

Even though there are many other famous desiccants such as activated alumina and molecular sieves silica gel is the usually used one because it has the high absorbing capacity. They are also very reasonable as compared to other famous desiccants. Further, its high adsorption nature and its cost silica gel are also extremely quick in its performance because as it absorbs moisture very quickly inside the packaging unit. It is unnecessary to say that silica gel chromatography for chemical separation is easier and simpler process for extrication components inside a given mixture.

Advantages of Silica Gels for Chromatography 

Benefits of Silica Gel Chromatography
Silica gel is known as an adsorbent that is used in various mesh sizes and is chosen on the basis of the water content which is there in the complexity and solution of the mixture. The size of the adsorbent involves the solvent’s flow all through the column chromatography procedure. The colored estranged compounds that are available in these desiccants are preordained to indicate the failure or success of the chromatography process. As soon as this procedure comes to a conclusion, the silica gel beads tend to change their color to know whether the moisture substance is dried up or it is not dried up. 

Few of the More Benefits Include:

•Best choosing of particle size for optimizing the competence
•Large surface area.
•Bulk quantities available and No scale-up limitations for large scale applications.
•Exceptional quality due to our closely restricted manufacturing process.
•Reproducible properties (physical, chemical, and structural).
•No scale-up limitation.
•There is less trace metal content.
•Controlled content for water level.
•High surface area and Neutral pH.
•No increased back-pressure or No clogging. 
•No particles going through contaminating final product and the filter.
•More stable, regular and reproducible chromatography.
•Quicker and more flow rate for good separation.
•There will be only improvement without any extra cost for you.
•Consistent and Reproducible retention for permitting straight scale up from industries  and laboratories through diverse process applications.


Applications Used For Silica Gel Chromatography:

• Steroids
• Organic compounds
• Dyes
• Amino acids
• Phenolic compounds
• Alkaloids
• Pharmaceutical intermediates

Comments

Post a Comment

Popular posts from this blog

BEST ABSORBENT FOR COLUMN CHROMATOGRAPHY

Image
Chromatography is a physical process, used to analyze the trace amounts of chemicals from a complex mixture. Chromatography is a valuable technique and gives accurate results, mainly because of the Silica Gel absorbent. In Chromatography, the most commonly used is Column Chromatography Technique. To avoid the loss of solvents volume and for reasonable separation, Adsorbent Silica gel chromatography is in great demand. Since Silica Gel has a closely controlled pore size, it allows the components of complex mixture to pass through the absorbent, based on the affinity. Strongly absorbed component by the Silica Gel remains on the top of the column, where as remaining components flow down in the Silica Gel column. About Silica gel Column Chromatography Silica Gel grades called as mesh, act as barrier and helps in determining the amount of single component present in a complex mixture. This Silica gel mesh absorbent is available with different labels based on the mesh size. The ...
Read more

Which Adsorbents Are Superior in Chromatography?

Image
Chromatography and Its Different Types Chromatography is a commonly used method for the separation and purification of different mixtures. It basically involves two steps- the mobile phase and the stationary phase. The chromatography process is explained as follows- at first the mixture, which has to be separated is dissolved in the liquid mobile phase and then placed on top of a vertical glass column. Then it is passed down the vertical column containing the solid stationary phase. As the mixture makes its journey downwards, different components will get separated at different levels. This is because different components move at different speeds and this is the reason behind their separation. The latter is also dependent on the differential partitioning between the mobile and stationary phases. Chromatography is broadly divided into  preparative and analytical. While preparative chromatography is used to isolate the components of any given mixture for further use, analyt...
Read more

Silica Gel Mesh for Column Chromatography

Image
Column chromatography is now regarded as one of the very significant and widely utilized techniques for the analysis and separation of complex organic mixtures. Silica gel for carrying out column chromatography is available in different particle size desired for pilot plant application. The silica gel 200-400 mesh size is ideal for flash chromatography, which means low pressure chromatography. The very smaller size particle of 200-400 mesh size offers better separation outcome with pressurized column. This is the very commonly utilized mesh size in places like organic synthesis labs. The silica gel of mesh size 200-300 is suited for achieving gravitational chromatography. The larger particle size of this silica gel enables solvent to smoothly flow without pressure besides offering excellent separation results. In column chromatography of 100-200 silica gel grade , a solid adsorbent and the stationary phase is placed in the vertical glass column and a liquid, the mobile pha...
Read more